Ibogaine is a psychoactive compound derived from the root bark of the Tabernanthe iboga plant, a shrub native to West Central Africa. For centuries, it has been used in ceremonial rites by the Bwiti spiritual tradition in Gabon to facilitate connection, healing, and self-discovery. In the West, ibogaine gained attention in the mid-20th century after anecdotal reports suggested it could interrupt addiction, alleviate withdrawal symptoms, and reduce cravings. 

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The modern history of ibogaine as a treatment is closely tied to the work of the late Howard Lotsof, who, in 1962, discovered its potential to address opioid addiction after experiencing a profound reduction in his own withdrawal symptoms. Lotsof spent the rest of his life advancing ibogaine research and lobbying for clinical trials. Despite promising early results, progress stalled due to regulatory hurdles, safety concerns, and the broader stigma surrounding psychedelics. Today, as the mental health crisis continues to devastate communities, we are committed to carrying forward Howard’s vision: safely, legally, and equitably bringing ibogaine to those who need it most, especially those most harmed by punitive U.S. drug policies.

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Ibogaine is more than a potential treatment for addiction; it represents a fundamental shift in how we understand and respond to human suffering. Its ability to work across biological, psychological, and spiritual dimensions offers hope to those trapped in cycles of despair. Yet this promise also comes with responsibility. Ibogaine requires careful medical oversight, as it can cause serious side effects, particularly cardiac risks. Its legal status in the United States continues to block research and access, making it all the more urgent to build evidence-based, community-informed pathways forward.

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The significance of ibogaine cannot be overstated at a time when overdose deaths are at record highs. As conventional treatments fail to reach or resonate with many, ibogaine offers the possibility of genuine healing and a renewed sense of purpose. By advancing rigorous research, supporting ethical clinical trials, and ensuring this medicine remains free from exploitation in the public domain, we can honor its origins and unlock its transformative potential to save lives and reshape our approach to addiction and recovery.